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Your vote counts Dice therapeutics inc. 2022 annual meeting vote by June 6,2022 11:59 pm et Dice therapeutics inc. 400 east Jamie court, suite #300 South San Francisco, ca 94080 D79558-p70666 You invested in dice therapeutics inc. and it’s time to vote! You have the right to vote on proposals being presented at the annual meeting. This is an important notice regarding the availability of proxy material for the shareholder meeting to be held on June 7,2022. Get informed before you vote View the notice and proxy statement and form 10-k online or you can receive a free paper or email copy of the material(s) by requesting prior to May 24, 2022. If you would like to request a copy of the material(s) for this and/or future shareholder meetings, you may (1) visit www.proxyvote.com, (2) call 1-800-579-1639 or (3) send an email to sendmaterial@proxyvote.com. If sending an email, please include your control number (indicated below) in the subject line. Unless requested, you will not otherwise receive a paper or email. copy. For complete information and to vote, visit www.proxyvote.com control #Smarthphone users point your camera here and vote without entering a control number Vote virtually at the meeting *June 7,2022 9:00a.m., pacific time Virtually at: www.virtualshareholdermeeting.com/dice2022


Vote at www proxyvote.com This is not a votable ballot This is an overview of the proposals being presented at the upcoming shareholder meeting. Please follow the instructions on the reverse side to vote these important matters. Voting items board recommends Election of directors Nominees:  Shaan c, Gandhi, M.D., D.Phil Lisa bowers Mittie Doyle, M.D. for for  2 to ratify the appointment of Ernst & young LLP as our independent registered public accounting firm for the fiscal year ending December 31,2022. Note: such other business as may properly come before the meeting or any adjournment thereof.    Prefer to receive an email instead? While voting on www.proxy.com, be sure to click “sign up for E-delivery”.   D79559-P70666